Kif1B Interacts with KBP to Promote Axon Elongation by Localizing a Microtubule Regulator to Growth Cones
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چکیده
منابع مشابه
Microtubule behavior in the growth cones of living neurons during axon elongation
To understand how microtubules are generated in the growth cone, we have imaged fluorescently tagged microtubules in living frog embryonic neurons. The neurons were labeled by injecting rhodamine-labeled tubulin into the fertilized egg and explanting the neurons from the neural tube. Microtubules extend deep into the growth cone periphery and adopt three characteristic distributions: (a) disper...
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Goldberg-Shprintzen syndrome (GOSHS) is a rare clinical disorder characterized by central and enteric nervous system defects. This syndrome is caused by inactivating mutations in the Kinesin Binding Protein (KBP) gene, which encodes a protein of which the precise function is largely unclear. We show that KBP expression is up-regulated during neuronal development in mouse cortical neurons. Moreo...
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هدف از این تحقیق بررسی برخی عوامل ادراکی واحساسی یعنی استفاده از شیوه های یادگیری زبان ، انگیزه ها ونگرش نسبت به زبان انگلیسی در رابطه با زمینه زبانی زبان آموزان می باشد. هدف بررسی این نکته بود که آیا اختلافی چشمگیر میان زبان آموزان دو زبانه و تک زبانه در میزان استفاده از شیوه های یادگیری زبان ، انگیزه ها نگرش و سطح مهارت زبانی وجود دارد. همچنین سعی شد تا بهترین و موثرترین عوامل پیش بینی کننده ...
15 صفحه اولMicrotubule organization in growth cones.
13. Albelda. S. M. & Huck. C. A. (1990) FASEH J. 4, 2868-2880 Kouslahti, E. (1001) J. Clin. Invest. 87. 1-’5 Hurridge. K., Fath, K., Kelly, T., Nuckolis, H. & Turner. C. (1988) Annu. Rev. Cell Hiol. 4, 487-525 Tamkun, J. W.. l)eSimone, I). W.. Fonda, I).? I’atel, K. S., Huck, C. A., Horwitz, A. F. & Hynes, K. 0. (1986) Cell (Cambridge. Mass.) 46,271-282 Springer, T. A. (1990) Nature (London) 34...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2016
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.0054-16.2016